ZART TABLET
November 10, 2017ZART FORTE TABLET
November 10, 2017ZART DP TABLET
| ZART DP TABLET | Artemether 40 mg & Lumefantrine 240 mg Tablets |
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| Composition : | Each un-coated tablet contains Artemether 40 mg & Lumefantrine 240 mg. |
| Indications : | For the treatment of uncomplicated cases of malaria due to Plasmodium falciparum in adults and children of 15 kg and above. |
| Contraindications : | It is contraindicated in: • Patients with known hypersensitivity to the active substances or to any of the excipients. • Patients with severe malaria according to WHO definition. • Metoprolol, imipramine, amitryptyline, clomipramine. • Patients with a family history of sudden death or of congenital prolongation of the QTc interval on electrocardiograms, or with any other clinical condition known to prolong the QTc interval. • Antiarrhythmics of classes IA and III, - Neuroleptics, antidepressive agents, - Macrolides, fluoroquinolones, imidazole and triazole antifungal agents, - terfenadine, astemizole,cisapride, flecainide |
| Adverse Effects : | Hypersensitivity, Decreased appetite, Sleep disorders, Insomnia, Headache, Dizziness, Paraesthesia, Ataxia, hypoaesthesia, Somnolence, Palpitations, Vomiting, Abdominal pain, Nausea, Diarrhoea |
| Dosage : | Dosage in Adult Patients (>16 years of age) A 3-day treatment schedule with a total of 6 doses is recommended for adult patients with a bodyweight of 35 kg and above Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice-daily (morning and evening) for the following 2 days (total course of 24 tablets). Dosage in Pediatric Patients 5 kg to less than 15 kg bodyweight: One tablet as an initial dose, 1 tablet again after 8 hours and then 1 tablet twice-daily (morning and evening) for the following 2 days (total course of 6 tablet 15 kg to less than 25 kg bodyweight: Two tablets as an initial dose, 2 tablets again after 8 hours and then 2 tablets twice-daily (morning and evening) for the following 2 days (total course of 12 tablets). 25 kg to less than 35 kg bodyweight: Three tablets as an initial dose, 3 tablets again after 8 hours and then 3 tablets twice-daily (morning and evening) for the following 2 days (total course of 18 tablets). 35 kg bodyweight and above: Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice-daily (morning and evening) for the following 2 days (total course of 24 tablets) |
