HICAINE INJECTION
November 10, 2017NANDRO INJECTION
November 10, 2017
| SYNTOCIN INJECTION |
Oxytocin Injecrtions |
| Composition : |
Each ml of solution contains 10 IU (16.7 micrograms) oxytocin. |
| Indications : |
Antepartum
– Induction of labour for medical reasons, e.g. in cases of post-term gestation, premature rupture of membranes, pregnancy-induced hypertension (pre-eclampsia).
− Stimulation of labour in hypotonic uterine inertia.
– Early stages of pregnancy as adjunctive therapy for the management of incomplete, inevitable, or missed abortion.
Postpartum
– During caesarean section, following delivery of the child.
– Prevention and treatment of postpartum uterine atony and haemorrhage.
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| Contraindications : |
Hypersensitivity to the active substance or to any of the excipients. It should not be used for prolonged periods in patients with oxytocin-resistant uterine inertia, severe pre-eclamptic toxaemia or severe cardiovascular disorders.
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| Adverse Effects : |
Headache, anorexia, nausea, vomiting and abdominal pain, lethargy, drowsiness, unconsciousness and grand-mal type seizures, low blood electrolyte concentration. |
| Dosage : |
Induction or enhancement of labor:
It should be administered as an intravenous (i.v.) drip infusion or, preferably, by means of a variable-speed infusion pump. For drip infusion it is recommended that 5 IU of Syntocinon be added to 500ml of a physiological electrolyte solution (such as sodium chloride 0.9%).
Incomplete, inevitable, or missed abortion:
5 IU by i.v. infusion (5 IU diluted in physiological electrolyte solution and administered as an i.v. drip infusion or, preferably, by means of a variable-speed infusion pump over 5 minutes), if necessary followed by i.v. infusion at a rate of 20 to 40 milliunits/minute.
Caesarean section:
5 IU by i.v. infusion (5 IU diluted in physiological electrolyte solution and administered as an i.v. drip infusion or, preferably, by means of a variable-speed infusion pump over 5 minutes) immediately after delivery.
Prevention of postpartum uterine haemorrhage:
The usual dose is 5 IU by i.v. infusion (5 IU diluted in physiological electrolyte solution and administered as an i.v. drip infusion or, preferably, by means of a variable-speed infusion pump over 5 minutes) after delivery of the placenta.
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